Plasma Concentrations of Afamin Are Associated With Prevalent and Incident Type 2 Diabetes: A Pooled Analysis in More Than 20,000 Individuals.
Barbara KolleritsClaudia LaminaCornelia HuthPedro Marques-VidalStefan KiechlIlkka SeppäläJackie CooperSteven C HuntChrista MeisingerChristian HerderLudmilla KedenkoJohann WilleitBarbara ThorandDoreen DähnhardtDoris StöcklKarin WilleitMichael RodenWolfgang RathmannBernhard PaulweberAnnette PetersMika KähönenTerho LehtimäkiOlli T RaitakariSteve E HumphriesPeter VollenweiderHans DieplingerFlorian KronenbergPublished in: Diabetes care (2017)
This pooled analysis in >20,000 individuals showed that afamin is strongly associated with IR, prevalence, and incidence of type 2 diabetes independent of major metabolic risk factors or parameters. Afamin might be a promising novel marker for the identification of individuals at high risk for the development of type 2 diabetes.