The diagnosis and management of subclinical hypothyroidism is assay-dependent- Implications for clinical practice.
Tejas R KalariaAnna SandersJonathan FennHelen L AshbyPervaz MohammedHarit N BuchClare FordRousseau GamaPublished in: Clinical endocrinology (2021)
The diagnosis and management of SCH is strikingly different when using TSH and fT4 assays provided by Abbott Laboratories and Roche Diagnostics. Clinicians and laboratorians should be aware that between-assay differences and variations in reference ranges will directly impact the diagnosis and management of subclinical hypothyroidism.