Epithelial-mesenchymal transition changes in nonsmall cell lung cancer patients with early COPD.
Wenying LuMathew Suji EapenAshutosh HardikarCollin ChiaIain RobertsonGurpreet Kaur SingheraTillie L HackettSukhwinder Singh SohalPublished in: ERJ open research (2023)
EMT is an active process in the small airway of smokers and COPD diagnosed with nonsmall cell lung cancer, contributing to small airway remodelling and cancer development as seen in these patients.
Keyphrases
- epithelial mesenchymal transition
- chronic obstructive pulmonary disease
- end stage renal disease
- single cell
- cell therapy
- lung function
- ejection fraction
- epidermal growth factor receptor
- newly diagnosed
- chronic kidney disease
- signaling pathway
- peritoneal dialysis
- papillary thyroid
- prognostic factors
- squamous cell carcinoma
- mesenchymal stem cells
- lymph node metastasis