Clinical, laboratory, and temporal predictors of neutralizing antibodies to SARS-CoV-2 after COVID-19.
Jim BoonyaratanakornkitChihiro MorishimaStacy SelkeDanniel ZamoraSarah McGuffinAdrienne E ShapiroVictoria L CampbellChristopher L McClurkanLichen JingRobin GrossJanie LiangElena PostnikovaSteven MazurAnu ChaudharyMarie K DasSusan L FinkAndrew B BryanAlex L GreningerKeith R JeromeMichael R HolbrookTerry B GernsheimerMark H WenerAnna WaldDavid M KoellePublished in: medRxiv : the preprint server for health sciences (2020)
Nab titers correlated with COVID-19 severity, age, and sex. Standard commercially available SARS-CoV-2 IgG results can serve as useful surrogates for nAb testing. Functional nAb levels were found to decline and a small proportion of COVID-19 survivors lack adaptive immune responses.