Facile synthesis of a cyclodextrin-metal organic framework decorated with Ketjen Black and platinum nanoparticles and its application in the electrochemical detection of ofloxacin.
Feng LuanYunfei WangShuang ZhangXuming ZhuangChunyuan TianXiuli FuLingxin ChenPublished in: The Analyst (2020)
A facile and novel method was developed to improve the conductivity of a cyclodextrin-metal organic frameworks (CD-MOFs) by modifying it with Ketjen Black (KB) and platinum nanoparticles (PtNPs). The structural morphology and composition of this PtNPs/KB/CD-MOFs nanocomposite was characterized by transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, elemental mapping, and Raman spectroscopy. The sensor was then evaluated for its ability to detect ofloxacin using cyclic voltammetry, and the results showed that the PtNPs/KB/CD-MOF had high sensitivity, satisfactory stability and good reproducibility. In addition, a great linear range was obtained with a concentration range of 0.08-100 μM and a low detection limit of 0.037 μM (S/N = 3). Therefore, the prepared electrochemical sensor could be successfully used to detect ofloxacin in serum.
Keyphrases
- metal organic framework
- electron microscopy
- label free
- raman spectroscopy
- ionic liquid
- high resolution
- gold nanoparticles
- reduced graphene oxide
- quantum dots
- loop mediated isothermal amplification
- nk cells
- real time pcr
- molecularly imprinted
- highly efficient
- mass spectrometry
- single molecule
- computed tomography
- capillary electrophoresis
- magnetic resonance imaging
- sensitive detection
- carbon nanotubes
- solid state