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Insulin-like growth factor 1 knockdown attenuates high glucose-induced podocyte injury by promoting the JAK2/STAT signalling-mediated autophagy.

Yun ZhangMin LiuYan WuYaling XuYuanhao HongHaiyan Xiang
Published in: Nephrology (Carlton, Vic.) (2024)
Knocking down IGF-1 alleviates HG-induced podocyte injury and apoptosis by inactivating the JAK2/STAT signalling pathway and enhancing autophagy.
Keyphrases
  • high glucose
  • endothelial cells
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • diabetic rats
  • cell proliferation
  • diabetic nephropathy
  • stress induced