Candidate gene associations reveal sex-specific Graves' disease risk alleles among Chinese Han populations.

Chen-Yan YanYu-Ru MaFeng SunRui-Jia ZhangYa FangQian-Yue ZhangFeng-Yao WuShuang-Xia ZhaoHuai-Dong Song

Published in: Molecular genetics & genomic medicine (2020)

The findings of this study suggest the existence of one potential sex-specific Graves' disease variant on Xq21.1. This could increase our understanding of the pivotal mechanism behind Graves' disease and ultimately aid in identifying possible therapeutic targets.

Keyphrases

genome wide
gene expression
dna methylation
risk assessment
transcription factor
human health