SIK2: A critical glucolipid metabolic reprogramming regulator and potential target in ovarian cancer.

Dan HuJunHong DuYiJuan XingYueMei ChengRuiFen HeXiaoLei LiangHongLi LiYongxiu Yang

Published in: The journal of obstetrics and gynaecology research (2023)

SIK2 displays significant effects in OC progression and treatment through regulating cellular metabolism including glucose and lipid metabolism. Therefore, future research needs to further explore the molecular mechanisms of SIK2 in other types of energy metabolism in OC, based on this to develop more unique and effective inhibitors.

Keyphrases

transcription factor
blood glucose
type diabetes
metabolic syndrome
risk assessment
current status
human health
skeletal muscle
weight loss