Effects of apalutamide dose reduction on skin-related adverse events in patients with advanced prostate cancer: A multicenter retrospective study.

Takuya OishiShingo HatakeyamaRyuji TabataDaiji FujimoriYohei KawashimaRyuma TanakaNoritaka IshiiHikari MiuraToshikazu TanakaTeppei OkamotoHayato YamamotoTakahiro YoneyamaYasuhiro HashimotoSatoshi SatoChikara Ohyama

Published in: The Prostate (2022)

Apalutamide dose reduction was not significantly associated with the incidence of skin-related AEs. However, dose reduction in patients with small body sizes may alleviate skin-related AEs without sacrificing oncological outcomes.

Keyphrases

prostate cancer
radical prostatectomy
metabolic syndrome
type diabetes
rectal cancer
skeletal muscle
insulin resistance