Naringenin mitigates titanium dioxide (TiO2)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB.

Marília F ManchopeNayara A ArteroVictor FattoriSandra S MizokamiDimitrius L PitolJoão P M IssaSandra Y FukadaThiago M CunhaJosé C Alves-FilhoFernando Q CunhaRubia CasagrandeWaldiceu Aparecido Verri

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2018)

Naringenin ameliorates TiO2-induced chronic arthritis inducing analgesic and anti-inflammatory responses with improvement in the histopathological index, cartilage damage, and bone resorption.

Keyphrases

oxidative stress
diabetic rats
high glucose
rheumatoid arthritis
drug induced
signaling pathway
dna damage
inflammatory response
pi k akt
soft tissue