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Functional Signature of LRP4 Antibodies in Myasthenia Gravis.

Omar ChuquisanaFrauke StascheitChristian W KellerMaja Pučić-BakovićAnne-Marie PatenaudeGordan LaucSocrates TzartosHeinz WiendlNick WillcoxAndreas MeiselJan D Lünemann
Published in: Neurology(R) neuroimmunology & neuroinflammation (2024)
LRP4-Abs are more effective in inducing cellular FcR-mediated effector mechanisms than Ab-dependent complement activation. Their functional signature is different from AChR-specific Abs.
Keyphrases
  • myasthenia gravis
  • regulatory t cells
  • dendritic cells