Understanding the interplay between APO E polymorphism and cognition in the Italian oldest old: results from the "Mugello study".

Gemma LombardiSilvia PancaniSilvia BagnoliFederica VannettiBenedetta NacmiasSandro SorbiFrancesca CecchiClaudio Macchi

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)

Results support that ApoE genotype no longer plays a role in the health condition of the oldest old, however, an interaction is detectable between ApoE polymorphism and cognitive performances at this extreme age.

Keyphrases

cognitive decline
high fat diet
healthcare
public health
mild cognitive impairment
mental health
climate change
white matter
health information
risk assessment
metabolic syndrome
human health