Inclusive Trial Designs in Acute Spinal Cord Injuries: Prediction-Based Stratification of Clinical Walking Outcome and Projected Enrolment Frequencies.
Adrian CathomenLaura SirucekTim KilleenRainer AbelDoris MaierNorbert WeidnerRüdiger RuppTorsten HothornJohn D SteevesArmin CurtMarc BolligerPublished in: Neurorehabilitation and neural repair (2022)
URP-CTREE enables inclusive trial design by revealing the distribution of outcome cohorts, discerning distinct recovery profiles and projecting potential patient enrolment by providing estimates of the relative frequencies of cohorts to improve the design of clinical trials in SCI and beyond.