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Corneal Confocal Microscopy Identifies Parkinson's Disease with More Rapid Motor Progression.

Sze Hway LimMaryam FerdousiAlise KaltenieceZiyad R MahfoudIoannis N PetropoulosRayaz A MalikChristopher KobyleckiMonty A Silverdale
Published in: Movement disorders : official journal of the Movement Disorder Society (2021)
CCM identifies neurodegeneration in patients with PD, especially those who show the greatest progression in neurological disability. CCM may be a useful tool to help enrich clinical trials with those likely to exhibit more rapid progression and reduce required sample size and cost of studies. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
  • clinical trial
  • genome wide
  • loop mediated isothermal amplification
  • systematic review
  • gene expression
  • open label
  • blood brain barrier
  • phase ii
  • study protocol
  • subarachnoid hemorrhage