Detection of circulating DNA for the diagnosis of invasive fusariosis: retrospective analysis of 15 proven cases.
Sarah DellièreJuliette GuitardMarcela SabouCécile AngebaultMaxime MoniotMarjorie CornuSamia HamaneMarie-Elisabeth BougnouxSébastien ImbertGrégoire PasquierFrançoise BotterelDea Garcia-HermosoAlexandra SerrisPublished in: Medical mycology (2022)
Fusariosis ranks third among invasive mould infections. It is frequently diagnosed late due to the lack of specific tools. We designed and evaluated a new qPCR assay with high sensitivity and specificity allowing detection of Fusarium DNA in serum samples up to 18 days before conventional diagnosis.