Regulation Network and Prognostic Significance of Aldo-Keto Reductase (AKR) Superfamily Genes in Hepatocellular Carcinoma.

Tianxing Dai Linsen YeHaoyuan YuKun LiJing LiRong-Qiang LiuXu LuMingbin DengRong LiWei LiuYang YangGuoying Wang

Published in: Journal of hepatocellular carcinoma (2021)

The dysregulated AKR genes could be mediated by DNA methylation and TFs in HCC. The risk model established with superior prognostic performance further suggested the significant role of AKR genes involved in the progression of HCC.

Keyphrases

genome wide
dna methylation
genome wide identification
bioinformatics analysis
gene expression
transcription factor