A diffuse glioma with oligodendroglial-like cells and extensive calcifications.

Filippo Maria MartelliElena MarastoniValeria Barresi

Published in: Brain pathology (Zurich, Switzerland) (2023)

The tumor showed extensive microcalcifications and cells with oval, nuclei and a clear perinuclear halo (A), positive immunostaining for OLIG-2 (B), GFAP (C), and CD34 (D), and intermingled Neu-N-positive neurons (E). FISH revealed multiple signals for the centromere of chromosome 7 (gains) (green probe) and the EGFR locus (red probe) (F, left), and a single signal for the centromere of chromosome 10 (loss) (F, right).

Keyphrases

induced apoptosis
living cells
small cell lung cancer
quantum dots
copy number
cell cycle arrest
spinal cord
tyrosine kinase
single cell
low grade
endoplasmic reticulum stress
oxidative stress
dna methylation
gene expression
fluorescent probe
genome wide association study
cell proliferation
pi k akt
high grade