Reduced rapid eye movement sleep in late middle-aged and older apolipoprotein E ɛ4 allele carriers.

Claire AndréMarie-Ève Martineau-DussaultAndrée-Ann BarilNicola Andrea MarchiVéronique DaneaultDominique LorrainCarol Hudon Célyne H BastienDominique PetitCynthia ThompsonJudes PoirierJacques MontplaisirNadia GosselinJulie Carrier

Published in: Sleep (2024)

Our results show that APOE4 carriers exhibit lower REM sleep duration, including in cognitively unimpaired individuals, possibly resulting from early neurodegenerative processes in regions involved in REM sleep generation and maintenance.

Keyphrases

physical activity
cognitive decline
sleep quality
high fat diet
mild cognitive impairment
middle aged
community dwelling
metabolic syndrome
adipose tissue