N-acetyl cysteine induces quiescent-like pancreatic stellate cells from an active state and attenuates cancer-stroma interactions.
Haimin FengTaiki MoriyamaKenoki OhuchidaNan ShengChika IwamotoKoji ShindoKengo ShirahaneNaoki IkenagaShuntaro NagaiKohei NakataKazuhiro MizumotoMasafumi NakamuraPublished in: Journal of experimental & clinical cancer research : CR (2021)
NAC suppressed activated PSCs and attenuated cancer-stromal interactions. NAC induces quiescent-like PSCs that were maintained in this state by pioglitazone treatment.