Symptomatic Patients with Hyperleukocytic FLT3-ITD Mutated Acute Myeloid Leukemia Might Benefit from Leukapheresis.
Kiavasch Mohammad Nejad FaridTim SauerMichael SchmittCarsten Müller-TidowAnita SchmittPublished in: Cancers (2023)
Among patients with clinical symptoms of leukostasis, the subset of FLT3-ITD mut AML patients showed a better outcome with lower early mortality after emergency LA. Based on these observations, we established a therapeutic algorithm for AML patients with hyperleukocytosis.
Keyphrases
- acute myeloid leukemia
- allogeneic hematopoietic stem cell transplantation
- end stage renal disease
- ejection fraction
- newly diagnosed
- emergency department
- chronic kidney disease
- public health
- healthcare
- machine learning
- peritoneal dialysis
- deep learning
- patient reported outcomes
- acute lymphoblastic leukemia
- neural network