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Circulating osteogenic proteins are associated with coronary artery calcification and increase after myocardial infarction.

Antonio Eduardo Pereira PesaroMarcelo KatzMarcel LibermanCarolina PereiraCristovão L P MangueiraAna Eduarda Zulim de CarvalhoKarina S CarvalhoCesar H NomuraMarcelo FrankenCarlos V Serrano
Published in: PloS one (2018)
Higher MGP and RANKL levels associate with CAC. These findings highlight the potential role of these proteins as modulators and markers of CAC. In addition, the post-MI increase in OPG and MGP, as well as of inflammatory proteins suggest that the regulation of these OPs is affected by atherothrombotic inflammation.
Keyphrases
  • coronary artery
  • oxidative stress
  • mesenchymal stem cells
  • small molecule
  • pulmonary artery
  • bone marrow
  • chronic kidney disease
  • immune response
  • risk assessment
  • nuclear factor
  • pulmonary hypertension
  • toll like receptor