Calcitriol inhibits osteoclastogenesis in an inflammatory environment by changing the proportion and function of T helper cell subsets (Th2/Th17).

Chun-Sheng BiXuan LiHong-Lei QuLi-Juan SunYing AnYong-Long HongBei-Min TianFa-Ming Chen

Published in: Cell proliferation (2020)

Calcitriol can inhibit osteoclastogenesis in an inflammatory environment by changing the proportion and function of Th cell subsets. Our findings suggest that calcitriol may be an effective therapeutic agent for treating periodontitis.

Keyphrases

single cell
cell therapy
oxidative stress
peripheral blood
dendritic cells
regulatory t cells
bone loss
inflammatory response
bone marrow