Antifungal activity of liriodenine on clinical strains of Cryptococcus neoformans and Cryptococcus gattii species complexes.
Adriele Dandara Levorato VincheMarcia de Souza Carvalho MelhemLucas Xavier BonfiettiIván de-la-Cruz-ChacónCarmen Sílvia Fernandes BoaroAlexandre Todorovic FabroGisela FerreiraJulhiany de Fátima da SilvaDaniela Carvalho Dos SantosBeatriz Aparecida Soares PereiraCamila MarçonLariza MazaLidia Raquel de CarvalhoRinaldo Poncio MendesPublished in: The journal of venomous animals and toxins including tropical diseases (2022)
injury observed by TEM, the absorption after gavage administration, and the safety at the tested doses indicate that the liriodenine molecule is a promising drug lead for development of anticryptococcal agents.
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