Accuracy of C-reactive Protein and Procalcitonin for Diagnosing Bacterial Infections Among Subjects With Persistent Fever in the Tropics.
Lukas Van DuffelCedric P YansouniJan JacobsMarjan Van EsbroeckKadrie RamadanJozefien BuyzeAchilleas TsoumanisBarbara BarbéMarleen BoelaertKristien VerdonckFrancois ChappuisEmmanuel BottieauPublished in: Open forum infectious diseases (2022)
In patients with persistent fever, CRP and PCT showed higher sensitivity for bacterial infections than WBC count, applying commonly used cutoffs for normal values. A normal CRP value excluded the vast majority of severe infections and could therefore assist in deciding whether to withhold empiric antibiotics after cautious clinical assessment.