Levels of oxidative stress biomarkers and bone resorption regulators in apical periodontitis lesions infected by Epstein-Barr virus.

Aleksandar Jakovljevic Miroslav AndricN NikolicV CoricS KrezovicJ CarkicA KnezevicK Beljic-IvanovicM Pljesa-ErcegovacM MileticI SoldatovicT RadosavljevicT JovanovicT SimicV IvanovicJ Milasin

Published in: International endodontic journal (2018)

Levels of bone resorption regulators and oxidative stress biomarkers were increased in apical periodontitis compared to healthy pulp tissues. EBV-positive periapical lesions exhibited higher levels of RANKL and OPG compared to EBV-negative periapical lesions. EBV may contribute to progression of apical periodontitis via enhanced production of bone resorption regulators.

Keyphrases

epstein barr virus
bone loss
oxidative stress
diffuse large b cell lymphoma
bone mineral density
transcription factor
soft tissue
dna damage
gene expression
ischemia reperfusion injury
induced apoptosis
postmenopausal women
body composition
immune response
nuclear factor
cone beam computed tomography
cone beam