Retroperitoneal ganglioneuroma presenting as lower back pain.
Kleoniki KordeniLeonidas ChardaliasEirini PantioraDimitris MassarasKonstantinos PapadopoulosElias PrimetisElissaios KontisGeorgios P FragulidisPublished in: Journal of surgical case reports (2022)
Retroperitoneal ganglioneuroma (RGN) is a rare benign tumor that arises from the retroperitoneal sympathetic ganglia composed of mature Schwann cells, ganglion cells and nerve fibers. These tumors can occur anywhere along the paravertebral sympathetic plexus and occasionally from adrenal medulla. Although they grow in excessive size, they may cause compression to adjacent organ or structures thus giving rise to symptoms. Resecting RGN's is a challenging endeavor, as they tend to encase neighboring vessels to their site of origin. The reported case is a 43-year-old male who presented with lumbar pain that increased progressively in intensity over the last 6 months. Preoperative investigations revealed a large tumor with encasement of the origins of the superior mesenteric artery and bilateral renal arteries. The tumor was completely resected and the final pathology confirmed the diagnosis of RGN.
Keyphrases
- induced apoptosis
- cell cycle arrest
- neuropathic pain
- robot assisted
- minimally invasive
- oxidative stress
- endoplasmic reticulum stress
- high resolution
- ultrasound guided
- signaling pathway
- peripheral nerve
- cell death
- weight gain
- pain management
- spinal cord injury
- body mass index
- mass spectrometry
- high intensity
- cell proliferation
- blood flow
- spinal cord
- pi k akt
- weight loss
- thoracic surgery