Beneficial effects of Hibiscus rosa-sinensis L. flower aqueous extract in pregnant rats with diabetes.

Luana Alves Freitas AfiuneThaís Leal-SilvaYuri Karen SinzatoRafaianne Queiroz Moraes-SouzaThaigra Sousa SoaresKleber Eduardo CamposRicardo Toshio FujiwaraEmilio HerreraDébora Cristina DamascenoGustavo Tadeu Volpato

Published in: PloS one (2017)

Our results demonstrate beneficial effects of this flower only in pregnant rats with diabetes and their offspring. Although these findings cannot be extrapolated to human clinical use, they show that the indiscriminate intake of H. rosa-sinensis may be harmful to healthy individuals and its use should be completely avoided in pregnancy.

Keyphrases

type diabetes
cardiovascular disease
glycemic control
endothelial cells
pregnant women
high fat diet
preterm birth
induced pluripotent stem cells
ionic liquid
metabolic syndrome
adipose tissue
pregnancy outcomes
weight loss