Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis.

Yujuan Liu Wenyu Li Ji Luo Yiguo Wu Yuanyuan Xu Ting-Tao Chen Wei Zhang Fen Fu

Published in: Disease markers (2021)

This study is the first to demonstrate that CRIP1 acts as an oncogene and may promote tumour metastasis by regulating the EMT-related Wnt/β-catenin signaling pathway, suggesting that CRIP1 may be an important biomarker for ovarian cancer metastasis and progression.

Keyphrases

epithelial mesenchymal transition
cell proliferation
stem cells
signaling pathway
protein protein
small molecule