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Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues.

Courtney W HannaRaquel Pérez-PalaciosLenka GahurovaMichael SchubertFelix KruegerLaura BigginsSimon AndrewsMaria Colomé-TatchéDeborah Bourc'hisWendy DeanGavin Kelsey
Published in: Genome biology (2019)
This study reveals distinct epigenetic mechanisms regulating non-canonical imprinted gene expression between embryonic and extra-embryonic development and identifies an integral role for ERVK LTR repetitive elements.
Keyphrases
  • gene expression
  • dna methylation
  • genome wide
  • high frequency