Diffusion Tensor Imaging Connectomics Reveals Preoperative Neural Connectivity Changes in Children with Postsurgical Posterior Fossa Syndrome.
Avner MeodedLisa JacobsonAnn LiuColleen BauzaThierry A G M HuismanNeil GoldenbergHoward WeinerGeorge JalloEric JacksonPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2020)
Our findings revealed significant differences in preoperative neural connectivity involving the corticothalamic and other pathways among children who did, versus who did not, develop PFS postoperatively. Diffusion tensor imaging connectomics offers a unique opportunity to study the effect of the posterior fossa tumors on cerebello-cerebral networks and provide new insights into the mechanism of the structural plasticity/reorganization after surgery.