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Interleukin 12 and interleukin 23 play key pathogenic roles in inflammatory and proliferative pathways in giant cell arteritis.

Richard ConwayLorraine O'NeillGeraldine M McCarthyConor C MurphyAurelie FabreSusan KennedyDouglas J VealeSarah M WadeUrsula FearonEamonn S Molloy
Published in: Annals of the rheumatic diseases (2018)
IL-12 and IL-23 play central and distinct roles in stimulating inflammatory and proliferative pathways relevant to GCA pathogenesis.
Keyphrases
  • giant cell
  • oxidative stress