Cytotoxicity Activity and Druggability Studies of Sigmasterol Isolated from Marine Sponge Dysidea avara Against Oral Epithelial Cancer Cell (KB/C152) and T-Lymphocytic Leukemia Cell Line (Jurkat/ E6-1).

Melika NazemiMostafa KhalediMahdi GolshanMasoud GhorbaniMohammad Reza AmiranAlireza DarvishiOmid Rahmanian

Published in: Asian Pacific journal of cancer prevention : APJCP (2020)

The compound showed desirable pharmacokinetic properties (ADME). This provided direct evidence of how a prospective anti-cancer agent can be stigmasterol. The preclinical studies paved the way for a potential new compound of anti-cancer.

Keyphrases

case control
acute myeloid leukemia
bone marrow
molecular docking
cell therapy
human health
risk assessment
molecular dynamics simulations