Arf6-driven endocytic recycling of CD147 determines HCC malignant phenotypes.

Shanshan QiLinjia SuJing LiChuanshan ZhangZhe MaGuiqiu LiuQing ZhangGuhe JiaYongjun PiaoSi-He Zhang

Published in: Journal of experimental & clinical cancer research : CR (2019)

Our results revealed that Arf6-mediated CD147 endocytic recycling is required for the malignant phenotypes of liver cancer. The Arf6-driven signaling machinery provides excellent biomarkers or therapeutic targets for the prevention of liver cancer.

Keyphrases

nk cells
single cell