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Treatment of Hyperthyroidism Reduces Systemic Oxidative Stress, as Measured by Markers of RNA and DNA Damage.

Camilla Bøgelund LarsenKamilla R RiisKristian H WintherEmil L LarsenChristina EllervikLaszlo HegedüsThomas H BrixHenrik E PoulsenSteen J Bonnema
Published in: The Journal of clinical endocrinology and metabolism (2021)
Restoration of euthyroidism in patients with hyperthyroidism significantly decreased the systemic oxidative stress load by 10% to 25%. Our findings may help to explain the higher morbidity and mortality linked to hyperthyroid diseases, as shown in observational studies.
Keyphrases
  • oxidative stress
  • dna damage
  • diabetic rats
  • ischemia reperfusion injury
  • induced apoptosis
  • dna repair
  • combination therapy
  • replacement therapy
  • drug induced
  • heat shock
  • smoking cessation
  • heat shock protein