Ratiometric photoacoustic imaging of endogenous HNO in vivo for assessing prodrug release and liver injury.

Xiaopeng FanHongzhen WangWen YangTian-Bing Ren Lin Yuan

Published in: Chemical communications (Cambridge, England) (2023)

The effective imaging of endogenous HNO is highly crucial for pathology research and medical development due to its important pharmacological activity in biological systems. Here, a ratiometric photoacoustic probe in response to HNO was rationally developed to effectively assess HNO prodrug release and liver injury in vivo .

Keyphrases

liver injury
drug induced
living cells
quantum dots
fluorescent probe
high resolution
fluorescence imaging
sensitive detection
cancer therapy
healthcare
hydrogen peroxide
drug release
energy transfer
nitric oxide
mass spectrometry