Autologous adipose-derived mesenchymal stem cell therapy reverses detrusor underactivity: open clinical trial.

Henrique Rodrigues Scherer CoelhoSilvia Cordeiro das NevesJovino Nogueira da Silva MenezesAndréia Conceição Milan Brochado Antoniolli-SilvaRodrigo Juliano Oliveira

Published in: Stem cell research & therapy (2023)

The results indicate that stem cell therapy led to improvements in voiding function. Cell therapy with adipose tissue-derived stem cells is safe and should be considered a new therapeutic option for the treatment of detrusor underactivity. Trial registration ISRCTN, ISRCTN23909398; Registered 15 March 2021-Retrospectively registered, https://doi.org/10.1186/ISRCTN23909398.

Keyphrases

cell therapy
stem cells
clinical trial
mesenchymal stem cells
adipose tissue
phase ii
phase iii
study protocol
botulinum toxin
umbilical cord
minimally invasive
open label
insulin resistance
type diabetes
double blind
combination therapy
skeletal muscle
smoking cessation