Novel positive allosteric modulator of protease-activated receptor 1 promotes skin wound healing in hairless mice.

Yohan SeoYunkyung HeoSungwoo JoSo-Hyeon ParkChulho LeeJiwon ChangDong-Kyu JeonTae Gun KimGyoonhee HanWan Namkung

Published in: British journal of pharmacology (2021)

Our results revealed that GB83 is the first positive allosteric modulator of PAR1 and it can be a useful pharmacological tool for studying PAR1 and a potential therapeutic agent for skin wound healing.

Keyphrases

wound healing
small molecule
single cell
type diabetes
metabolic syndrome