MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway.

Huizhi WangJingyu MinYuntao DingZhengyue YuYujing ZhouShunyu WangAihua GongMin Xu

Published in: Biological procedures online (2024)

MBD3 promoted migration, invasion, proliferation and EMT by upregulating ACTG1 via PI3K/AKT signaling activation in GC cells and may be a potential diagnostic and prognostic target.

Keyphrases

signaling pathway
epithelial mesenchymal transition
pi k akt
cell cycle arrest
induced apoptosis
transforming growth factor
cell death
cell proliferation
cell migration
oxidative stress