Untargeted metabolomic profiling of serum from dogs with chronic hepatic disease.
Yuri A LawrenceMicah A BishopJulia B HonnefferAudrey K CookAline Rodrigues-HoffmannJoerg M SteinerJan S SuchodolskiJonathan A LidburyPublished in: Journal of veterinary internal medicine (2019)
The serum metabolome varies among healthy dogs, dogs with congenital portosystemic shunts, and dogs with chronic hepatitis. Statistical analysis identified several metabolites that differentiated healthy dogs from dogs with vascular or parenchymal liver disease. Further targeted assessment of these metabolites is needed to confirm their diagnostic reliability.