In vitro anti-HIV activity of some Indian medicinal plant extracts.

Aparna PalshetkarNavin PathareNutan JadhavMegha PawarAshish WadhwaniSmita KulkarniKamalinder K Singh

Published in: BMC complementary medicine and therapies (2020)

These active methanolic extracts of Achyranthes aspera and Rosa centifolia, could be further subjected to chemical analysis to investigate the active moiety responsible for the anti-HIV activity. Methanolic extract of Rosa centifolia was found to be well tolerated maintaining the epithelial integrity of HEC-1A cells in vitro and thus has potential for investigating it further as candidate microbicide.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
induced apoptosis
men who have sex with men
oxidative stress
cell cycle arrest
south africa
endoplasmic reticulum stress
cell death
climate change
anti inflammatory
cell wall
drug discovery