Preliminary Promising Findings for Manganese Chloride as a Novel Radiation Countermeasure Against Acute Radiation Syndrome.
Maureen N HoodEmmanuel AyompeGregory P Holmes-HamptonAlexandru KorotcovKefale WuddieZemenu AschenakeAnwar E AhmedMarqus CreavalleBarbara Knollmann-RitschelPublished in: Military medicine (2024)
Initial experiments show that MnCl2 is a promising safe and effective prophylactic countermeasure against ARS. MRI data support the systemic distribution of MnCl2 which is needed in order to protect multiple tissues in the body. The pathology data in bone marrow and the brain support faster recovery from radiation exposure in the treated animals and decreased organ damage.
Keyphrases
- bone marrow
- electronic health record
- big data
- liver failure
- mesenchymal stem cells
- magnetic resonance imaging
- gene expression
- drug induced
- oxidative stress
- white matter
- contrast enhanced
- respiratory failure
- radiation induced
- resting state
- computed tomography
- magnetic resonance
- case report
- data analysis
- machine learning
- hepatitis b virus
- aortic dissection
- newly diagnosed
- deep learning
- diffusion weighted imaging
- brain injury
- radiation therapy
- blood brain barrier