Dilatatone, a new chlorinated compound from Parmotrema dilatatum.

Hoang-Vinh-Truong PhanAsshaima Paramita DeviHoang-Duy LeThanh-Trung NguyenHuu-Hung NguyenTran-Thai-Duong LeTai Hoang NguyenJirapast Sichaem Thuc-Huy Duong

Published in: Natural product research (2020)

Chemical investigation of the lichen Parmotrema dilatatum led to the isolation of a new chlorinated compound, named dilatatone (1), along with a known compound, sernanderin (2). Their chemical structures were determined by analysis of their 1 D and 2 D NMR spectra, HRESIMS, and ECD data. Both compounds showed weak α-glucosidase inhibitor activity.

Keyphrases

high resolution
magnetic resonance
polycyclic aromatic hydrocarbons
electronic health record
gas chromatography
molecular docking
density functional theory
big data
machine learning
deep learning
tandem mass spectrometry