Life-threatening dermatoses: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. Impact on the Spanish public health system (2010-2015).
Virginia Velasco-TiradoMontserrat Alonso-SardónAdriana Cosano-QueroÁngela Romero-AlegríaLeire Sánchez-Los ArcosAmparo López-BernusJavier Pardo-LledíasMoncef Belhassen-GarcíaPublished in: PloS one (2018)
Older patients have a more severe clinical picture and higher mortality rates. The overall mortality of both diseases is approximately 10%, and clinical diagnosis and age were the variables with the greatest influence on mortality. This study describes a stable incidence and a similar prevalence to other European countries. Additionally, the data show a high cost due to hospitalizations. Finally, the CMBD could be a good system of epidemiological analysis for the study of infrequent diseases and hospital management of conditions such as SJS and TEN.