SOX18 meditates the resistance of Bmi1-expressing cells to cetuximab in HNSCC.

Caihua Zhang Zhi ChenNailin GaoGan XiongPeng ChenHui LiDemeng Chen Qianting HeLiang Peng

Published in: Oral diseases (2023)

Taken together, the findings of our study suggest that Sox18 mediates the resistance of Bmi1-expressing cells to cetuximab in HNSCC via the oxidative phosphorylation pathway.

Keyphrases

induced apoptosis
cell cycle arrest
body mass index
stem cells
endoplasmic reticulum stress
oxidative stress
squamous cell carcinoma
wild type
locally advanced
metastatic colorectal cancer
physical activity
weight loss