Cortical mapping of callosal connections in healthy young adults.
Yirong XiongLiyuan YangChangtong WangChenxi ZhaoJunhao LuoDi WuYiping OuyangMichel de Thiebaut de SchottenGaolang GongPublished in: Human brain mapping (2024)
The corpus callosum (CC) is the principal white matter bundle supporting communication between the two brain hemispheres. Despite its importance, a comprehensive mapping of callosal connections is still lacking. Here, we constructed the first bidirectional population-based callosal connectional atlas between the midsagittal section of the CC and the cerebral cortex of the human brain by means of diffusion-weighted imaging tractography. The estimated connectional topographic maps within this atlas have the most fine-grained spatial resolution, demonstrate histological validity, and were reproducible in two independent samples. This new resource, a complete and comprehensive atlas, will facilitate the investigation of interhemispheric communication and come with a user-friendly companion online tool (CCmapping) for easy access and visualization of the atlas.
Keyphrases
- white matter
- single cell
- diffusion weighted imaging
- young adults
- functional connectivity
- high resolution
- multiple sclerosis
- resting state
- high density
- social media
- subarachnoid hemorrhage
- magnetic resonance imaging
- contrast enhanced
- molecular dynamics
- cerebral ischemia
- wastewater treatment
- magnetic resonance
- healthcare
- health information
- single molecule