Immune biomarkers and anti-HIV activity in the reproductive tract of sexually active and sexually inactive adolescent girls.

Mimi GhoshMariel JaisRoshni BiswasJason JarinJason DanielsChristopher JoyMonika JuzumaiteVanessa EmmanuelVeronica Gomez-Lobo

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2018)

Higher pro-inflammatory biomarker TNF-α, as well as a distinct inflammation-associated immune clustering in sexually inactive girls, can potentially increase risk for infections including HIV upon sexual debut. Future studies with larger sample sizes are needed to characterize the immune parameters associated with sexual activity.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
human immunodeficiency virus
hiv testing
hepatitis c virus
hiv aids
mental health
men who have sex with men
rheumatoid arthritis
single cell
rna seq
current status
south africa