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COL1A1 proximal promoter topology regulates its transcriptional response to transforming growth factor β.

Elena HitrayaSvetlana GaidarovaSonsoles Piera-VelazquezSergio A Jimenez
Published in: Connective tissue research (2024)
The topology of the COL1A1 proximal promoter is crucial in determining the transcriptional activity of the gene and its response to the stimulatory effects of TGF-β1.
Keyphrases
  • transforming growth factor
  • transcription factor
  • gene expression
  • epithelial mesenchymal transition
  • dna methylation
  • genome wide identification
  • genome wide
  • copy number
  • heat shock
  • oxidative stress