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Resorcin[4]arene-based multidentate phosphate ligands with superior binding affinity for nanocrystal surfaces.

Suren J NematDietger Van den EyndenLoren DeblockMichael HeilmannJesper M KösterMahsa ParvizianKonrad TiefenbacherJonathan De Roo
Published in: Chemical communications (Cambridge, England) (2021)
We designed and synthesized two resorcin[4]arene scaffolds with four phosphate binding groups. The ligands effectively bind in at least a tridentate fashion at low surface coverage. The superior binding affinity is demonstrated using solution NMR spectroscopy and exceeds that of single phosphonates.
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