Use of benznidazole to treat chronic Chagas disease: An updated systematic review with a meta-analysis.

Clara Crespillo-AndújarBelén ComecheDavidson H HamerIngrid Arevalo-RodriguezNoelia Alvarez-DíazJavier ZamoraJosé Antonio Pérez-Molina

Published in: PLoS neglected tropical diseases (2022)

Benznidazole should be recommended for CCD in children, though this is only based on serological response and a moderate grade of evidence, while in adults benznidazole efficacy remains uncertain. More data on clinical efficacy of benznidazole in CCD is needed in both children and adults.

Keyphrases

trypanosoma cruzi
systematic review
young adults
meta analyses
electronic health record
high intensity
machine learning
big data
data analysis