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Inhibitory Potential of Phytochemicals on Interleukin-6-Mediated T-Cell Reduction in COVID-19 Patients: A Computational Approach.

Arif MalikAnam NazSajjad AhmadMansoor HafeezFaryal Mehwish AwanTassadaq Hussain JafarAyesha ZahidAqsa IkramBisma RauffMubashir Hassan
Published in: Bioinformatics and biology insights (2021)
It has been predicted that proposing potential IL-6 inhibitors with less side effects can help critical COVID-19 patients because it may control the cytokine storm, a major responsible factor of its pathogenesis. In this study, 3 potential phytocompounds have been proposed to have inhibitory effect on IL-6 that can be tested as potential therapeutic options against SARS-CoV-2.
Keyphrases
  • sars cov
  • human health
  • respiratory syndrome coronavirus
  • risk assessment