Inhibitory Potential of Phytochemicals on Interleukin-6-Mediated T-Cell Reduction in COVID-19 Patients: A Computational Approach.
Arif MalikAnam NazSajjad AhmadMansoor HafeezFaryal Mehwish AwanTassadaq Hussain JafarAyesha ZahidAqsa IkramBisma RauffMubashir HassanPublished in: Bioinformatics and biology insights (2021)
It has been predicted that proposing potential IL-6 inhibitors with less side effects can help critical COVID-19 patients because it may control the cytokine storm, a major responsible factor of its pathogenesis. In this study, 3 potential phytocompounds have been proposed to have inhibitory effect on IL-6 that can be tested as potential therapeutic options against SARS-CoV-2.